The Centre of New Technologies invites to a webinar by

Małgorzata Firczuk PhD,

Department of Immunology, Center of Biostructure, Medical University of Warsaw

Title: Novel, targeted therapy of B-cell malignancies with poor prognosis

Date: 15th January 2021 (Friday)

Time: 12:00 pm (Central European Time)

Host: prof. Marta B. Wiśniewska

Virtual seminar: https://us02web.zoom.us/j/86338374810

CeNT-UW-Webinars-instruction-for-attendees

Abstract:

B cell malignancies are a heterogeneous group of diseases derived from B cell precursors at various stages of B cell development and from mature B cells. We have established a multidisciplinary consortium to study novel therapeutic options for patients with B cell malignancies at preclinical stage. During the talk I will present results of our ongoing projects regarding novel therapeutic options that we develop against poorly-treated, high-risk subtypes of B cell acute lymphoblastic leukemia. They include targeting enzymes involved in redox metabolism, the combination treatment composed of thioredoxin inhibitors and venetoclax, as well as novel immunotherapeutic options. I will also explain our in vitro, ex vivo and in vivo models, highlighting the crucial role of the close collaboration of our research team with clinicians.

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