Seminars archive
The Centre of New Technologies invites to a seminar by
prof. Marek Cieplak
Head of Laboratory of Biological Physics, Institute of Physics, Polish Academy of Sciences
Title: „Interbasin traffic and emergence of knots in intrinsically disordered proteins”
Date: November 15th, 2019 at 12 p.m.
Venue: Centre of New Technologies, Banacha 2C,
Lecture Hall 0142 (Ground floor)
Host: prof. Joanna Trylska and prof. Dariusz Plewczyński
Abstract:
The equilibrium dynamics of the intrinsically disordered proteins is thought to consist of transitions between many basins in the free energy landscape whereas structured proteins stay in the vicinity of one native basin. We demonstrate this picture explicitly by studying networks defined on the discretized plane: conformational end-to-end distances vs. radii of gyration. The bin sizes are defined by time scales that span orders of magnitude. The networks, derived from all-atom and coarse-grained molecular dynamics simulations, are nearly scale invariant. The bin representation also provides insights into the folding proces of the structured proteins and identifies regions of hindrance to folding. Transient knotted structures are expected to arise during the volatile evolution of intrinsically disordered peptide chains. We show that this is indeed the case for sufficiently long polyglutamine tracts and α-synuclein. The polyglutamine tracts are fused within huntingtin protein that is associated with the Huntington neurodegenerative disease. We show that the presence of knots in the tracts hinders and sometimes even jams translocation, especially when the knots are deep. The knots in polyglutamine may form in tracts exceeding about 40 residues. This fact explains the existence of a similarly sized length treshold above which there is an experimentally observed toxicity at the monomeric level. We also discuss emergence of knots in α-synuclein. We show that these knots are either shallow or deep and last for about 3 – 5 µs, as inferred from an all-atom explicit-solvent 20 and 30 µs trajectories. We discuss conformational biasses that take place in α-synuclein and contact formation during association of two chains of this protein.
In collaboration with: M. Chwastyk, Ł. Mioduszewski, B. de Aquino, A. Gomez-Sicilia, M. Carrion-Vazquez, P. Robustelli.
The Centre of New Technologies invites to a seminar by
Dr. Sarah Knowles
Research Fellow at the Department of Zoology, University of Oxford,
United Kingdom
What makes a microbiome? Ecological and evolutionary forces shaping the gut microbiota in wild mammals
Date: September, 25th (Wednesday), 2019 at 12 p.m.
Venue: Centre of New Technologies, Banacha 2C,
Lecture Hall 0142 (Ground floor)
Host: Prof. Marta Szulkin
Please see the attachment for more details.
The Centre of New Technologies invites to a seminar by
Dima Kozakov, PhD
Stony Brook University, Department of Applied Mathematics and Statistics
Efficient sampling and optimization on manifolds for macromolecular docking
Date: July, 17th (Wednesday), 2019 at 12.30 p.m.
Venue: Centre of New Technologies, Banacha 2C,
Lecture Hall 0142 (Ground floor)
Host: dr. hab Joanna Sułkowska
Please see the attachment for more details.
The Centre of New Technologies invites to a seminar by
Jung-Shin Lee Ph.D.
Department of Molecular Bioscience, College of Biomedical Sciences, Kangwon National University, Kangwondaehak-gil, Chuncheon-si, Gangwon-do, 24341 Republic of Korea
Transcriptional regulation by methylation of the fourth lysine on histone H3 in yeasts
Date: July, 15th (Monday), 2019 at 12 p.m.
Venue: Centre of New Technologies, Banacha 2C,
Lecture Hall 0142 (Ground floor)
Host: Prof. Magda Konarska
For more details, please see the attachment.
The Centre of New Technologies invites to a seminar by
Prof. Alfredo Ferro
Department of Clinical and Experimental Medicine, University of Catania
Computational pathway analysis and simulation in cancer
Date: June, 28th (Friday), 2019 at 12 p.m.
Venue: Centre of New Technologies, Banacha 2C,
Lecture Hall 0142 (Ground floor)
Host: Dr. Marta Dudek
For more details, please see the attachment.
ReMedy International Research Agenda invites to a special lecture:
„Liquid-type condensates in transcription and RNA splicing”
by
Prof. Phillip A. Sharp
Institute Professor and Professor of Biology, Member,
Koch Institute for Integrative Cancer Research,
Massachusetts Institute of Technology, Cambridge, MA
June 7th, 2019, 12:00 pm
CeNT UW, Banacha 2C, Lecture Hall 0142
Host: Magda Konarska
The Centre of New Technologies invites to a seminar by
Prof. Stefan Dziembowski
Faculty of Mathematics, Informatics and Mechanics, University of Warsaw
Crypto in Crypto
Date: May, 31st (Friday), 2019 at 12 p.m.
Venue: Centre of New Technologies, Banacha 2C,
Lecture Hall 0142 (Ground floor)
Host: Prof. Marta B. Wiśniewska
For more details, please see the attachment.
The Centre of New Technologies invites to a seminar by
Dawid Walerych, PhD
How mutant p53 and the proteasome machinery reshape transcriptomes and proteomes of cancer cells
Date: March 1st, 2019 at 12 p.m.
Venue: Centre of New Technologies, Banacha 2C,
Lecture Hall 0142 (Ground floor)
Host: Marta B. Wiśniewska
For more details please see the attachment.
The Centre of New Technologies invites to a seminar by
Dr. Sebastian Glatt
Malopolska Centre of Biotechnology (MCB), Jagiellonian University
Charging the Code – Insights into tRNA Modification Enzymes
Date: February, 22nd (Friday), 2019 at 12 p.m.
Venue: Centre of New Technologies, Banacha 2C,
Lecture Hall 0142 (Ground floor)
Host: Prof. Agnieszka Chacińska
For more details, please see the attachment.
The Centre of New Technologies of the University of Warsaw
invites to a seminar by
Prof. Gianluca Tell
University of Udine
„Non canonical roles of BER enzymes in RNA processing: novel perspectives in cancer biology through the study of APE1 protein – and RNA –interactomes. ”
January, 25th (Friday), 2019 at 12 p.m.
Venue: Centre of New Technologies, Banacha 2C
Lecture Hall 0.142 (Ground floor)
Host: Dr. Carlo Vascotto
For more details, please see the attachment.
The Centre of New Technologies
invites to a seminar by
Dr. Łukasz Szatkowski,
University of Cincinnati
„Mechanical stability of microtubule lattices – molecular dynamic indentation studies”
Date: January 14th, 2019 at 12 p.m.
Venue: Centre of New Technologies, Banacha 2C,
Lecture Hall 0142 (Ground floor
Host: dr hab. Joanna Sułkowska
For more details, please see the attachment.
The Centre of New Technologies invites to a seminar by
Prof. Anna Ciemerych-Litwinienko,
University of Warsaw (Biology Department)
„From Pluripotency to Myogenesis”
Date: January 11th, 2019 at 12 p.m.
Venue: Centre of New Technologies, Banacha 2C,
Lecture Hall 0142 (Ground floor)
Host: Marta B. Wiśniewska
For more details, please see the attachment.
All are welcome.
The Centre of New Technologies invites to a seminar by
Prof. Pavel Jungwirth
Institute of Organic Chemistry and Biochemistry of Chech Academy of Sciences
Biological Water or Rather Water in Biology?
4th of December 2018 at 2 p.m.
Venue: Centre of New Technologies, Banacha 2C,
Lecture Hall 0142 (Ground floor)
Host: Dr. Piotr Setny
For more details, please see the attachment.
A kind reminder about the upcoming seminar by Dr Remigiusz Serwa, on „Proteomics Core Facility @CeNT”.
The event is scheduled for November 30th, 2018 at 12 p.m. in room 00.142.
For more details, please see the attachment.
All are welcome.
The Centre of New Technologies invites to a seminar by
Magdalena Winiarska, PhD
Medical University of Warsaw
Tumor microenvironment – a key barrier to effective anti-tumor immune response.
23rd of November 2018 at 12 p.m.
Venue: Centre of New Technologies, Banacha 2C,
Lecture Hall 0142 (Ground floor)
Host: Marta B. Wiśniewska
For more details, please see the attachment.
A kind reminder about the upcoming seminar by Dr. Alexander Schug, on „Simulating the molecular machinery of life”.
The event is scheduled for November 15th, 2018 at 12 p.m. in room 00.142.
Please note that this week the seminar will be held on Thursday, that is tomorrow.
For more details, please see the attachment.
All are welcome.
We would like to invite you to an upcoming seminar by Dr. Peter Virnau, on „Knots in DNA, Chromosomes and Polymer Melts”.
The event is scheduled for November 9th, 2018 at 12 p.m.
For more details, please see the attachment.
All are welcome.
We would like to invite you to an upcoming seminar by Prof. Ian Collinson, „Mechanism of protein translocation through the bacterial Sec machinery”.
The event is scheduled for October 24th, 2018 (Wednesday) at 12 p.m.
For more details, please see the attachment.
All are welcome.
We would like to invite you to an upcoming seminar by Prof. Marek Tchórzewski, on „The ribosomal GTPase-associated center as regulatory element modulating ribosomal modus operandi”.
The event is scheduled for October 18th, 2018 at 12 p.m.
For more details, please see the attachment.
All are welcome.
We would like to invite you to an upcoming seminar by Prof. Jose Luis Ferran, on „Brain induced changes in motor responses and fat tissue content during a forced exercise program in rodents”.
The event is scheduled for October 12th, 2018 at 12 p.m.
For more details, please see the attachment.
All are welcome.
We would like to invite you to an upcoming seminar by Prof. Jacek A. Majewski, on „New opportunities in the flat world”.
The event is scheduled for October 5th, 2018 at 12 p.m.
For more details, please see the attachment.
All are welcome.
We would like to invite you to an upcoming seminar by Prof. Tomasz J. Nowakowski, (University of California, San Francisco) on „Area-Specific Excitatory Neuron Development in the Human Cerebral Cortex”.
The event is scheduled for September 28th, 2018 at 12 p.m.
For more details, please see the attachment.
All are welcome.
We would like to invite you to an upcoming seminar by Kamil Tokár, PhD (Institute of Physics, Slovak Academy of Sciences; Faculty of Materials Science and Technology, Slovak University of Technology) on „2D Phosporene: modelling of complexity”.
The event is scheduled for 22nd of August at 12.30 p.m.
For more details, please see the attachment.
All are welcome.
We would like to invite you to the seminar by Prof. Yoshihisa Yamamoto (Japan Science and Technology Agency/Stanford University) on „Physics of quantum-to-classical crossover and coherent Isingmachines”.
The event is scheduled for 5th July at 12 p.m.
For more details, please see the attachment.
All are welcome.
We would like to invite you to an upcoming seminar by Prof. Matthias Bochtler (International Institute of Molecular and Cell Biology in Warsaw; The Institute of Biochemistry and Biophysics) on „The vocabulary of protein-DNA interactions: Symmetry, degeneracy, modifications”.
The event is scheduled for 14th of June at 12 p.m.
For more details, please see the attachment.
All are welcome.
We would like to invite you to an upcoming seminar by prof. Jose’ Lorenzana (Italian National Research Council, Sapienza University of Rome) on „Optical properties of quantum antiferromagnets”.
The event is scheduled for 15th of June at 12.30 pm.
For more details, please see the attachment.
All are welcome.
We would like to invite you to an upcoming seminar by Ewa K. Stachowiak (State University of New York at Buffalo) on „Neurodevelopment origins of schizophrenia – new lessons from induced Pluripotent Stem Cells”.
The event is scheduled for 7th June at 12 p.m.
For more details, please see the attachment.
All are welcome.
We would like to invite you to an upcoming seminar by Edward H. Egelman (Department of Biochemistry & Molecular Genetics, University of Virginia) on „Cryo-EM of Helical Protein and Nucleoprotein Polymers at Near-Atomic Resolution”.
The event is scheduled for 28th of May(Monday) at 12pm.
For more details, please see the attachment.
All are welcome.
We would like to invite you to an upcoming seminar by Bartosz Wilczyński (Institute of Informatics, University of Warsaw) on „Looking at chromosomal contacts at different scales”.
The event is scheduled for 17th of May at 12pm.
For more details, please see the attachment.
All are welcome.
We would like to invite you to an upcoming seminar by Victor Tybulewicz (The Francis Crick Institute, UK) on „Novel signalling pathways controlling T cell adhesion and migration”.
The event is scheduled for 10th of May at 12pm.
For more details, please see the attachment.
All are welcome.
Up-to-date list of seminars can be found in the Seminars tab.