Job offer for a PhD student position
02 grudnia 2019Position of PhD student in the project entitled „Modelling of crystal and magnetic local structure in potential quantum spin liquid (QSL) alpha-RuCl3” financed by National Science Centre (NCN) is open for application. Project leader: dr Wojciech Sławiński. Deadline for applications: 15 December 2019. For more info see >> pdf
An announcement for post-doc position
26 listopada 2019Position of post-doc (adiunkt) (a group of science positions) in the project entitled “From ion-selective nanofibers optical and electrochemical sensors towards „lab on a mat”” financed by National Science Centre, Poland, is open for application. Project leader: prof. dr hab. Agata Michalska-Maksymiuk. Deadline for applications: 15 January 2020. For more info see >> pdf
An announcement for post-doc position
Position of post-doc (adiunkt) (a group of science positions) in the project entitled “From ion-selective nanofibers optical and electrochemical sensors towards „lab on a mat”” financed by National Science Centre, Poland, is open for application. Project leader: prof. dr hab. Agata Michalska-Maksymiuk. Deadline for applications: 15 January 2020. For more info see >> pdf
An announcement for post-doc position
Position of post-doc (adiunkt) (a group of science positions) in the project entitled „Electrochemical systems with bipolar electrodes” financed by National Science Centre, Poland, is open for application. Project leader: prof. dr hab. Krzysztof Maksymiuk. Deadline for applications: 15 January 2020. For more info see >> pdf
4EU+ information meeting at UW
25 listopada 2019
All members of the UW community are invited to take part in the 4EU+ information meeting, which will take place on 5th December in the Old Library building. Participants will find out about the possibilities for students, doctoral candidates, and employees.
The 4EU+ Alliance, with the University of Warsaw as its member, is among the consortia selected for funding in the first pilot ‘European Universities’ call for proposals, launched as part of the 2019 Erasmus+ programme. The European Commission announced the results in June this year. On 7th-8th November, in Brussels, the European University Initiative was officially launched. More information >>
The most important information regarding the 4EU+ Alliance, flagship programmes, and the European University Initiative will be presented during the meeting.
The event is open to everyone:
- Students and doctoral candidates who want to find out more about education projects and research-based education within 4EU+,
- UW employees who would like to work together with other 4EU+ universities in terms of education, research, and innovation.
The 4EU+ information meeting will take place on 5th December at 9:00-11:30 in the Old Library building (aula).
The idea of the European University, according to the European Commission, is to bring together a new generation of creative Europeans able to cooperate across languages, borders and disciplines to address societal challenges and skills shortages faced in Europe. European Universities are transnational alliances of higher education institutions from across the EU that share a long-term strategy and promote European values and identity.
Source: www.en.uw.edu.pl
Seminar CeNT 29.11.2019
The Centre of New Technologies invites to a seminar by
Paulina Kasperkiewicz-Wasilewska, PhD
Faculty of Chemistry, Wrocław University of Science and Technology
Title: New Methods For Imaging Serine Proteases Involved In Cell Death Induction
Date: November, 29th (Friday) 2019 at 12 p.m.
Venue: Lecture Hall 0142 (ground floor)
Host: Prof. Joanna Trylska
Abstract:
Growing interest in NK and CTLs in target killing has made it imperative to develop new tools to measure the early events in pathogen elimination and targeted cell death. So far selective and potent functional small chemical tools for granzymes had not been discovered and only antibody related techniques are used in Grzs investigation, however they label total protein amount and cannot distinguish between active and inactive form of enzyme.
To overcome these limitations, we have developed innovative Grzs chemical tools that can be used to find answers for important, questioned functions of Grzs, which still remain controversial. These tools were used for imaging of Granzyme A and Granzyme B, enzymes involved in cell death induction, monitoring of their location and changes upon stimulation.
Seminar CeNT 22.11.2019
18 listopada 2019The Centre of New Technologies invites to a seminar by
Prof. Yuji Sugita
Chief Scientist at RIKEN Research Center in Tokyo, Japan
Title: Free-energy landscapes of protein-ligand bindings along the positional and orientational ligand coordinates
Date: November, 22nd (Friday), 2019 at 12 p.m.
Venue: Centre of New Technologies, Banacha 2C,
Lecture Hall 1130 (1st floor)
Host: Prof. Joanna Trylska
Abstract:
Protein-ligand binding is a slow process in solution and in a living cell. In the current study, we focus on the process between the encounter complex state and the canonical binding pose. Using all-atom MD simulations with enhanced conformational sampling algorithms, we could simulate the binding and unbinding events about hundred times. This simulation is sufficient to describe the free-energy landscape of protein-ligand binding processes. We observed the landscapes along the position coordinates as well as those along the ligand orientation coordinates. The former is a funnel like shape, while the latter is a more rugged „fork-shape” landscape. Based on the landscapes, we discuss molecular mechanisms for protein-ligand binding in solution.
Seminar CeNT 15.11.2019
12 listopada 2019The Centre of New Technologies invites to a seminar by
prof. Marek Cieplak
Head of Laboratory of Biological Physics, Institute of Physics, Polish Academy of Sciences
Title: „Interbasin traffic and emergence of knots in intrinsically disordered proteins”
Date: November 15th, 2019 at 12 p.m.
Venue: Centre of New Technologies, Banacha 2C,
Lecture Hall 0142 (Ground floor)
Host: prof. Joanna Trylska and prof. Dariusz Plewczyński
Abstract:
The equilibrium dynamics of the intrinsically disordered proteins is thought to consist of transitions between many basins in the free energy landscape whereas structured proteins stay in the vicinity of one native basin. We demonstrate this picture explicitly by studying networks defined on the discretized plane: conformational end-to-end distances vs. radii of gyration. The bin sizes are defined by time scales that span orders of magnitude. The networks, derived from all-atom and coarse-grained molecular dynamics simulations, are nearly scale invariant. The bin representation also provides insights into the folding proces of the structured proteins and identifies regions of hindrance to folding. Transient knotted structures are expected to arise during the volatile evolution of intrinsically disordered peptide chains. We show that this is indeed the case for sufficiently long polyglutamine tracts and α-synuclein. The polyglutamine tracts are fused within huntingtin protein that is associated with the Huntington neurodegenerative disease. We show that the presence of knots in the tracts hinders and sometimes even jams translocation, especially when the knots are deep. The knots in polyglutamine may form in tracts exceeding about 40 residues. This fact explains the existence of a similarly sized length treshold above which there is an experimentally observed toxicity at the monomeric level. We also discuss emergence of knots in α-synuclein. We show that these knots are either shallow or deep and last for about 3 – 5 µs, as inferred from an all-atom explicit-solvent 20 and 30 µs trajectories. We discuss conformational biasses that take place in α-synuclein and contact formation during association of two chains of this protein.
In collaboration with: M. Chwastyk, Ł. Mioduszewski, B. de Aquino, A. Gomez-Sicilia, M. Carrion-Vazquez, P. Robustelli.
An announcement for post-doc position
08 listopada 2019Position of postdoc (a research position) in the EURAMET (EMPIR) Project 18SIB04 „Towards quantum-based realizations of the pascal”, financed by the European Union’s Horizon 2020 research and innovation program, is open for application. Project leader: Prof. dr. Bogumił Jeziorski. Deadline for applications: 8 December 2019. For more info see >> pdf
Space International Information Day & Brokerage Event
07 listopada 2019
On 13th-14th November the “Space International Information Day & Brokerage Event” will take place at the University of Warsaw. The aim of the event is to present the funding opportunities in Horizon 2020 Space and to provide first-hand information on the last Horizon 2020 Space Calls.
The “International Horizon 2020 Space Information Day and Brokerage Event” in Warsaw will be an opportunity to discuss with the authors of the Space Work Programme 2020 and get some important information concerning H2020 proposal writing.
The meeting is organised by the H2020 Space NCP Network – COSMOS2020plus, the National Contact Point for Research Programmes of the European Union in Poland and the University of Warsaw with the support of the European Commission.
There will also be a chance to take part in the international brokerage event, offering the possibility to conclude new international cooperation technology, business and research partnerships for the last SPACE Calls.
The “Space International Information Day & Brokerage Event” will take place on 13th-14th November in the Old Library building. The registration is open until 11th November.
Source: www.en.uw.edu.pl